The Natural Course of Unruptured Cerebral Aneurysms in a Japanese Cohort

The natural history of unruptured cerebral aneurysms has not been clearly defined. Methods From January 2001 through April 2004, we enrolled patients with newly identified, unruptured cerebral aneurysms in Japan. Information on the rupture of aneurysms, deaths, and the results of periodic follow-up examinations were recorded. We included 5720 patients 20 years of age or…