Severe depression may be treated with deep Brain stimulation DBS

Deep brain stimulationAssessment of deep brain stimulation for patients with treatment-resistant depression has inched forward over the past decade with promising results but remains in its early days with a total worldwide experience of roughly 60 patients.

That total includes patients who have received deep brain stimulation (DBS) leads placed in six different brain regions. However, the results suggest that one of the better target locations for DBS in patients with treatment-resistant depression (TRD) is in the nucleus accumbens, Dr. Bruno Millet said at the annual congress of the European College of Neuropsychopharmacology.

“The nucleus accumbens is a very good target that we will continue to study. It is very safe, and the surgery is easy and rapid. The nucleus accumbens has a good benefit-to-risk ratio,” said Dr. Millet, professor of psychiatry at the University of Rennes (France). “This is a strength of this target.”

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CPAP May Ease Depression

By Ed Susman, Contributing Writer, MedPage Today

Published: June 14, 2012.
Reviewed by Zalman S. Agus, MD; Emeritus Professor, Perelman School of Medicine at the University of Pennsylvania and Dorothy Caputo, MA, BSN, RN, Nurse Planner

Obstructive sleep apnea patients who use — or even try to use — continuous positive airway pressure (CPAP) devices appear to reduce their overall depressive symptom scores, researchers said here.

In every category measured, patients reduced depressive symptoms, even if they were not using the CPAP devices as prescribed, Charles Bae, MD, of the Cleveland Clinic College of Medicine at Case Western Reserve University told attendees at the annual meeting of the Associated Professional Sleep Societies. [Read more…]